WebProstaglandin D2 (0.36 nmol) was more effective in enhancing sleep at the later period of the infusion period. Uridine (10 pmol) caused a mild but long-lasting increase in sleep, especially in paradoxical sleep. Thus, each substance exhibited compound-specific sleep-modulating properties. http://healthysleep.med.harvard.edu/healthy/science/how/external-factors
Differential sleep-promoting effects of five sleep substances ... - PNAS
WebJul 16, 2024 · Acutely, cannabis is sleep-promoting and decreases latency, increases sleep time, increases slow-wave sleep, and decreases REMs [ 1, 23 ]. Consistent with this, CB1 antagonists increase... WebApr 11, 2024 · This study investigated the sleep-promoting effects of extracts of various hop (Humulus lupulus L.) varieties in invertebrate and vertebrate models. The content of α-acids, β-acids, and xanthohumol was higher in hop 70% alcohol extracts than in hop hot water extracts. Among the alcohol extracts, Citra contained a high α-acid content (229.32 ... elephant bag charm
Stimulants and Sleep - News-Medical.net
WebFeb 1, 2004 · Study objectives: The pharmacologic profile of modafinil, an increasingly popular wake-promoting drug for narcolepsy treatment, differs from those of classic psychostimulants such as amphetamine. However, its brain targets are still a matter of debate. We hypothesized that modafinil could increase waking by inhibiting the sleep … WebThe Delta sleep-inducing peptide (DSIP) is a naturally occurring substance isolated from a rabbit back in 1977. This substance is a nonpeptide which is synthesized in the hypothalamus and targets different sites like the brainstem. Suggested by its name, the Delta Sleep-Inducing Peptide promotes sleep, which has been demonstrated in: Rabbits … WebFeb 22, 2024 · Instead, moderate quality evidence now demonstrates that 5HT neurons promote wake. 5HT directly excites other wake-promoting neurons, and drugs that increase 5HT tone, such as SSRIs, generally increase wakefulness in both humans and rodents. elephant ball disease