Shld2
Web17 Jun 2024 · The observation that SHLD2 or MAD2L2 siRNAs caused sensitivity to ART558 in a BRCA1 mutant cell line raised the possibility that a Polθ inhibitor could be used to … WebSHLD2 (previously annotated as FAM35AandRINN2) as an effector of REV7 in the NHEJ pathway. FAM35A depletion impairs NHEJ-mediated DNA repair and compromises antibody diversification by class switch recombination (CSR) in B cells. FAM35A accumulates at DSBs in a 53BP1-, RIF1-, and REV7-dependent manner and antago-nizes HR by limiting …
Shld2
Did you know?
WebPurified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in … WebWhat are other names for "SHLD2 Antibody - C-terminal region (ARP57322_P050)"? This target may also be called "RINN2, FAM35A, FAM35A1, bA163M19.1" in publications. What is the shipping cost for "SHLD2 Antibody - C-terminal region (ARP57322_P050)"? The shipping cost for this item is $40 within the US.
WebKnockdown your target gene function with confidence. The patented modification pattern for specificity, combined with the SMARTselection algorithm for efficient, guaranteed target … WebSHLD2 INFORMATION. Proteini. Full gene name according to HGNC. Shieldin complex subunit 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. SHLD2 (bA163M19.1, FAM35A, FAM35A1, MGC5560, RINN2) Protein classi. Assigned HPA protein class (es) for the encoded protein (s).
WebView mouse Shld2 Chr14:33958990-34032450 with: sequences, polymorphisms, proteins, references, function Web1 Mar 2003 · Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex …
Web8 Apr 2024 · Preformed REV7-SHLD3 at 100 nM was incubated with 100 nM SHLD2. Similar rates were observed with addition of either 100 nM REV7WT(red) or REV7core (green). h Schematic of the proposed Shieldin ...
WebIF and ICC. Reactivity: Homo sapiens (Human), Mus musculus (House mouse), and Rattus norvegicus (Rat) SHLD2 Antibody - N-terminal region : Biotin (ARP57321_P050-Biotin) … rawahel transportWebHomepage Annals of Rheumatic Diseases raw agent in python assignment expertWebSHLD2 is part of cluster 67 Non-specific - Mitochondria & RNA binding with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated … simple character definitionWebNX_Q86V20 - SHLD2 - Shieldin complex subunit 2 - Function. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) … simple changes to end chronic painWebThe SHLD2 short isoform cDNA was obtained from the ORFeome collection. The complete coding sequence of the long isoform of SHLD2 was generated by combining a synthesized fragment corresponding to the long isoform C-terminus using an internal KpnI site. simple changes horseWeb8 Apr 2024 · The Shieldin complex represses end resection at DNA double-strand breaks (DSBs) and thereby serves as a pro-non homologous end joining (NHEJ) factor. The molecular details of the assembly of Shieldin and its recruitment to DSBs are unclear. Shieldin contains two REV7 molecules, which have the rare a … simple chapter books for early readersWeb11 Jun 2024 · The Shieldin complex represses end resection at DNA double-strand breaks (DSBs) and thereby serves as a pro-non homologous end joining (NHEJ) factor in the G1 … raw agent means