WebMay 24, 2010 · Background Connective Tissue Growth Factor (CTGF/CCN2), a known matrix-associated protein, is required for the lactogenic differentiation of mouse mammary epithelial cells. An HC11 mammary epithelial cell line expressing CTGF/CCN2 was constructed to dissect the cellular responses to CTGF/CCN2 that contribute to this … WebConnective tissue growth factor (CCN2, also termed CTGF) is one of six structurally related molecules that comprise the CCN family. 1 CCN proteins regulate cell function (for example, cell cycle progression, division, chemotaxis, differentiation, apoptosis, adhesion, gene regulation, ion transport) by interacting contextually with cell surface receptors, …
Goat anti-CTGF IgG blocks TGF-stimulation of collagen
WebNov 4, 2016 · CTGF is a matricellular, multifunctional protein that can influence the activity of multiple major signaling pathways, affecting cell adhesion, migration, proliferation, and differentiation. CTGF expression increases after central nervous system (CNS) trauma in rodents, but its function after spinal cord injury has not been elucidated ( 7 – 9 ). WebAug 15, 2009 · A rapid and dramatic reduction in the gene encoding connective tissue growth factor (CTGF) was observed in three-dimensional collagen culture. Connective tissue growth factor (CTGF) is a secreted molecule with many functions. It has been shown to participate in fibrogenesis, migration, proliferation, and adhesion 20-22. navigate mouse between two monitors
CTGF in kidney fibrosis and glomerulonephritis Inflammation and ...
WebJul 12, 2014 · Connective tissue growth factor (CTGF)/CCN family member 2 (CCN2) is a CCN family member of matricellular signaling modulators. It has been shown that CCN2/CTGF mediates cell adhesion, aggregation and migration in a large variety of cell types, including vascular endothelial cells, fibroblasts, epithelial cells, aortic smooth … WebFeb 25, 2024 · Connective tissue growth factor (CTGF/CCN2) belongs to the CCN family (Connective tissue growth factor [CTGF], Cystein ... MI in rodents and open-chest cardiac surgery in patients can damage the pericardium and may induce pericardial adhesions. CTGF mAb therapy during the proliferative phase of infarct repair might have had an … WebOct 29, 2024 · Connective tissue growth factor (CTGF) is a key signaling and regulatory molecule involved in different biological processes, such … navigate my care wegmasn