WebTable 2 summarizes 17 cases of biotin interference with susceptible thyroid assays described to date in the literature. Table 2 Summary of Case Reports Describing Biotin Interference on Thyroid and Parathyroid Immunoassays a,b. ... Repeat labs 1 month after biotin discontinuation once again revealed an elevated PTH. In a subsequent case, a ... WebJul 20, 2024 · Newer-generation assays now prevent biotin interference for TSH testing . Thyroid function tests consistent with hyperthyroidism and a positive radioactive iodine uptake (RAIU) scan: In a 34-year-old female with a history of anxiety and depression, while taking biotin supplements. Her labs normalized after stopping biotin .
Assessment of biotin interference in thyroid function tests
WebJun 21, 2024 · The FDA has issued an updated safety communication, UPDATE: The FDA Warns that Biotin May Interfere with Lab Tests, that discusses concerns with biotin interference in certain laboratory tests and ... WebJan 13, 2024 · The majority of these cases involved biotin interference with thyroid-stimulating hormone (TSH) and other thyroid-function tests; the rest involved other endocrine tests, such as parathyroid hormone (PTH), adrenocorticotropic hormone, prolactin, testosterone, and cortisol. ... The FDA warns that biotin may interfere with lab … dana haley plumbing and heating
Hypothyroidism (underactive thyroid) - Diagnosis and treatment
WebResults: The recent, marked, increase in the use of over-the-counter, high-dose biotin supplements has been accompanied by a steady increase in the number of reports of analytical interference by exogenous biotin in the immunoassays used to evaluate endocrine function. Since immunoassay methods of similar design are also used for the … WebApr 10, 2024 · Thyroid Hormone Measurements. Figure 2 shows the complexity of thyroid hormone metabolism, whereby the thyroid gland is the source of all circulating T4 but only ∼20% of triiodothyronine (T3). T3 has the highest avidity for thyroid nuclear receptors—10-fold higher than T4, the T3 metabolite Triac 4 also has some metabolic activity, 5 … WebAssessment of biotin interference in thyroid function tests. The aim of the study was to systematically characterize the interference of biotin on thyroid function tests and … birds clearance